Technical Specifications
Testing Indicators
| Test Item | Standard |
|---|---|
| Content | 99% Min. |
| Loss on Drying | 0.5% Max. |
| Appearance | Yellow Powder |
Basic Information
| Product Alias | DHP; Pyrimidine |
| English Name | 4,6-Dihydroxypyrimidine |
| Molecular Formula | C₄H₄N₂O₂ |
| Molecular Weight | 112.09 |
| CAS Number | 1193-24-4 |
| Packaging | 25 kg bag, or as per customer request. |
| Storage | Store in a dry and ventilated warehouse, avoid direct sunlight, stack lightly, handle with care. |
Product Introduction
Product Overview
4,6-Dihydroxypyrimidine (DHP) is a yellow powder, CAS 1193-24-4, molecular formula C₄H₄N₂O₂, molecular weight 112.09, content ≥99%. It is an organic synthesis intermediate used in the pharmaceutical industry to produce sulfonamide drugs, synthesize vitamin B4, and for antitumor drugs and auxiliary drug synthesis.
Product Features
- Assay ≥99%, high purity quality assurance
- Loss on drying ≤0.5%, low moisture content
- Pharmaceutical-grade purity with stable quality
- Pyrimidine compound with two hydroxyl groups in its structure
- Compatible with various organic synthesis reactions
- Widely used in pharmaceutical intermediates
Chemical Properties
4,6-Dihydroxypyrimidine is a pyrimidine derivative with a pyrimidine ring structure and two hydroxyl groups at the 4 and 6 positions. This symmetrical structure gives it unique chemical properties, making it an important heterocyclic intermediate in various organic synthesis reactions and a key raw material for synthesizing drugs containing pyrimidine ring structures.
Application Areas
Organic Synthesis Intermediate
Used as a key organic synthesis intermediate for pyrimidine compound synthesis and process development.
Sulfonamide production
Used in the synthesis of sulfonamide antibiotics, serving as a key raw material in their production.
Vitamin B4 synthesis
Used in the synthesis process of Vitamin B4 (adenine).
Antitumor Drug
Used in the synthesis of anticancer drugs and adjuvant medications, with important applications in oncology drug development.
- Store in a dry and ventilated warehouse, avoid direct sunlight
- Stack lightly, handle with care, avoid package damage
- Keep packaging sealed before and after use
FAQ
This product has 4,6-dihydroxypyrimidine content ≥99%, tested by HPLC or GC to ensure pharmaceutical-grade purity. Each batch undergoes strict quality inspection before shipment.
Loss on drying ≤0.5% is a key indicator of moisture content. Low loss on drying ensures stability during storage and use, preventing caking or quality degradation from moisture absorption.
The molecular formula of 4,6-dihydroxypyrimidine is C₄H₄N₂O₂, molecular weight 112.09. Its structure is a symmetrical pyrimidine ring with hydroxyl substituents at the 4 and 6 positions. This symmetrical structure gives it unique chemical properties, allowing it to participate in various organic synthesis reactions.
4,6-Dihydroxypyrimidine appears as a yellow powder, related to the conjugated double bond system in its molecular structure. The conjugated system formed by the pyrimidine ring and hydroxyl groups causes selective absorption of visible light, resulting in a yellow color. Low-color (low impurity) products should have a uniform yellow appearance.
4,6-Dihydroxypyrimidine is slightly soluble in water, soluble in hot water, alkali solutions, and some organic solvents. Its solubility is significantly affected by pH, increasing under alkaline conditions. As an amphoteric compound, it reacts with both acids and bases.
Under proper storage conditions (dry, ventilated, protected from direct sunlight), the product has a shelf life of up to 24 months. It is recommended to store in an indoor environment at 15-25°C, keep packaging sealed, and prevent moisture absorption and caking. Handle with care during stacking to avoid package damage.
When handling, wear protective gloves and a mask to avoid dust inhalation and skin contact. In case of contact with eyes or skin, rinse immediately with plenty of water. Use as a pharmaceutical intermediate in a GMP-compliant environment. Refer to the product MSDS for detailed safety information.
Pyrimidine compounds are a class of heterocyclic compounds containing a pyrimidine ring (1,3-diazine). 4,6-Dihydroxypyrimidine is characterized by hydroxyl substituents at the 4 and 6 positions of the pyrimidine ring, giving it unique reactivity. Compared to other pyrimidine compounds, its symmetrical structure and dihydroxy properties make it irreplaceable in certain synthetic routes.
Standard packaging: 25 kg/bag, paper bag with inner plastic liner for moisture protection. Custom packaging available upon request, such as fiber drums or plastic pails. IBC totes offered for bulk orders.
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