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Technical specifications
Control Parameters
| Test Parameters | Standard |
|---|---|
| Content | 99% Min. |
| Loss on drying | 0.5% Max. |
| Appearance | Yellow Powder |
Basic Information
| Alternative Product Name | DHP; pyrimidine |
| English name | 4,6-Dihydroxypyrimidine |
| Chemical Formula | C₄H₄N₂O₂ |
| Molecular weight | 112.09 |
| CAS No. | 1193-24-4 |
| Packaging | 25 kg bags or as per customer request. |
| Storage | Store in a dry, well-ventilated warehouse, protect from direct sunlight, stack neatly, handle with care. |
Product description
Product overview
4,6-Dihydroxypyrimidine (DHP) is a yellow powder, CAS 1193-24-4, molecular formula C₄H₄N₂O₂, molecular weight 112.09, content ≥99%. It is an organic synthesis intermediate used in the pharmaceutical industry for the production of sulfonamide drugs, vitamin B4 synthesis, and the synthesis of antitumor and adjuvant drugs.
Product Features
- Content ≥99%, guaranteed high purity quality
- Loss on drying ≤0.5%, low moisture content.
- Pharmaceutical Grade Application, Stable Purity
- Pyrimidine class compounds containing two hydroxyl groups in the structure.
- Can participate in various organic synthesis reactions
- Widely used in the field of pharmaceutical intermediates
Chemical Properties
4,6-Dihydroxypyrimidine is a pyrimidine derivative; its molecule contains a pyrimidine ring with two hydroxyl groups at positions 4 and 6. This symmetrical structure gives it unique chemical properties, allowing it to serve as an important heterocyclic intermediate in various organic synthesis reactions. It is a key raw material for the synthesis of drugs containing a pyrimidine ring.
Area of application
Organic synthesis intermediates
Important organic synthesis intermediate, used for synthesis and development of pyrimidine compounds.
Production of Sulfonamide Preparations
Used for the synthesis of sulfonamide antibacterial drugs; it is a key raw material for the production of this drug group.
Synthesis of Vitamin B4
Used in the synthesis process of vitamin B4 (adenine)
Antitumor drugs
Used in the synthesis of antitumor and adjuvant drugs, playing an important role in the development of anticancer medications.
- Store in a dry, well-ventilated area, avoid direct sunlight.
- Neat stacking, careful handling, avoid damaging packaging
- Keep packaging sealed before and after use
Frequently asked questions
Product content of 4,6-dihydroxypyrimidine ≥99%. Purity control is carried out by HPLC or GC methods, meeting pharmaceutical standards. Each batch undergoes strict quality control before shipment.
Loss on drying ≤0.5% is a key indicator of product moisture content. A low value indicates minimal water content, ensuring stability during storage and use, preventing caking and quality deterioration.
The molecular formula of 4,6-dihydroxypyrimidine is C₄H₄N₂O₂, molecular weight 112.09. Its structure is a symmetric pyrimidine ring with hydroxyl substituents at positions 4 and 6. This symmetric structure gives it unique chemical properties, allowing it to participate in various organic synthesis reactions.
4,6-Dihydroxypyrimidine appears as a yellow powder, which is due to the conjugated double bond system in its molecular structure. The conjugated system formed by the pyrimidine ring and hydroxyl groups leads to selective absorption of visible light, giving the compound a yellow color. Low-color (low-impurity) product should have a uniform yellow shade.
4,6-Dihydroxypyrimidine is slightly soluble in water, soluble in hot water, alkalis, and some organic solvents. Its solubility is highly pH-dependent, increasing in alkaline conditions. As an amphoteric compound, it reacts with both acids and bases.
Under proper storage conditions (dry, ventilated place, protected from direct sunlight), product shelf life can reach 24 months. Recommended storage indoors at 15-25°C, in sealed packaging, to avoid moisture absorption and caking. When storing, handle with care to avoid damaging packaging.
Use protective gloves and a respirator when handling; avoid inhaling dust and skin contact. In case of accidental contact with eyes or skin, rinse immediately with plenty of water. Use as a pharmaceutical intermediate under conditions meeting GMP requirements. For detailed safety information, refer to the product's Material Safety Data Sheet (MSDS).
Pyrimidines are heterocyclic compounds containing a pyrimidine ring (1,3-diazabenzene). 4,6-Dihydroxypyrimidine is characterized by hydroxyl substituents at positions 4 and 6 of the pyrimidine ring, giving it unique reactivity. Compared to other pyrimidines, its symmetrical structure and the presence of two hydroxyl groups make it indispensable in certain synthetic processes.
Standard packaging: 25 kg/bag, paper bags with PE liner for moisture protection. Custom packaging such as cardboard drums and plastic containers is also available upon customer request. IBC containers offered for large purchases.
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